Tag Archive | chemotherapy

LabBook February 22, 2013

LabBook February 22, 2013

Futuristic supply rooms, off label chemotherapy and more in this week’s special Move Day edition of LabBook

UChicago Researchers Establish Benchmark for Off-Label Use of Expensive Cancer Drugs

UChicago Researchers Establish Benchmark for Off-Label Use of Expensive Cancer Drugs

Health economics researchers led by Rena Conti, PhD, assistant professor of pediatrics at the University of Chicago, established a benchmark for the rate at which common chemotherapy treatments are used “off label.”

Drug target may cede malignant role to promiscuous little sister

The wonder drug Herceptin targets a cell-surface molecule known as HER-2, which is overexpressed in more than 20 percent of invasive breast cancers. High levels of HER2 are associated with aggressive tumors and reduced survival. In those patients, Herceptin, often combined with chemotherapy, can increase response rates and survival. But for many patients the benefits […]

LabBook August 24, 2012

Welcome to LabBook, our weekly roundup of University of Chicago Medicine & Biological Sciences research news from around campus and the world wide web. Each Friday, LabBook will recap the week on the blog, link to news stories about our faculty and studies, and briefly summarize a handful of recent publications by our researchers. This […]

A Warning for Childhood Cancer Survivors

As the hundreds of people at last weekend’s Cancer Survivors Day event could attest, overcoming cancer is a hard-earned victory. Unfortunately, double jeopardy laws don’t apply to cancer, and a patient who has beaten the disease once must remain vigilant about its potential return. A new study of people who survived cancer during their childhood […]

A Nano-Vehicle to Fight Brain Cancer

By Rob Mitchum Treating a brain tumor in a lab dish is easy. Scientists have developed a full arsenal of treatments to kill tumor cells, using natural toxins, chemotherapeutic drugs, and even gene therapy to send them to an early grave. But making those therapies work in the actual setting of the brain is a […]

Halting Cancer’s Evolution with Synthetic Lethality

In nature, species evolve thanks to those lucky organisms who cheat death. An environmental pressure may come in and kill of a high percentage of critters, but those critters who survive the bloodbath live on to spread their genes. When this bottle-necking occurs in disease-causing bacteria, we call it drug resistance: an antibiotic may knock […]

Dr. FAQ: Gary Steinberg on Bladder Cancer

On the grim top 10 list of the most common cancers in the United States, familiar faces sit at the top of the charts. Prostate cancer for men, breast cancer for women, lung and colon cancer for both sexes – all are diseases that have inspired massive awareness and fundraising efforts to inform patients and […]

The Cancer Drug That Needs a Cuff

There’s no such thing as a perfect drug. Physicians know that for every treatment benefit a drug provides, there will also be side effects that must be taken into consideration. Ideally, these side effects can be controlled with careful dosing of the drug or close monitoring of the patient, such that the drug’s good side […]

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