Tag Archive | drug design

A New Model for Anxiety…and More

by Rob Mitchum An advantage and disadvantage of hypothesis-free studies looking for genes associated with various traits or diseases is that they often point to genetic candidates that don’t make immediate sense. One example of this occurrence was the 2005 discovery of an association between the gene Glo1 and anxiety-like behaviors in mice. Previously, scientists […]

Hacking the Brain’s Security System

by Rob Mitchum The brain is a privileged organ, afforded protections denied to all the other organs of the body. Though the circulatory system functions much the same way above and below the neck, using blood to exchange nourishment for waste with cells, the exchange is conducted under much heavier security in the central nervous […]

Testing Treatments in the Anorexic Mouse

Anorexia nervosa is one of the most common psychiatric disorders, and also the deadliest. But unlike depression, anxiety, or schizophrenia, no drugs are approved for the treatment of patients with this eating disorder. Non-pharmacological interventions, such as family-based treatment or cognitive-behavioral therapy, remain the gold standard for helping patients get back to healthy eating habits […]

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