LabBook April 25, 2014

Staff from Gift of Hope visited ICU units at UChicago Medicine on Donate Life Blue & Green Day to thank staff for their work supporting organ transplants, on April 11, 2014. The Stories of Hope exhibits, shown here, feature photos and personal stories of organ donors and recipients.

Staff from Gift of Hope visited ICU units at UChicago Medicine on Donate Life Blue & Green Day to thank staff for their work supporting organ transplants, on April 11, 2014. The Stories of Hope exhibits, shown here, feature photos and personal stories of organ donors and recipients.

This week’s rundown of recent research publications of note from University of Chicago scientists and physicians:

[Re]considering Respect for Persons in a Globalizing World: Aasim Padela — Developing World Bioethics, April 11, 2014

From the abstract: “Contemporary clinical ethics was founded on principlism, and the four principles: respect for autonomy, nonmaleficence, beneficence and justice, remain dominant in medical ethics discourse and practice … The purpose of this analysis is to highlight challenges in assessing ethical behaviour according to the principlist model. We next describe cultural expectations and mores that inform both patient and clinician behaviors in these scenarios in order to argue that the principle of respect for persons informed by culture-specific ideas of personhood may offer an improved ethical construct for analyzing and guiding medical practice in a globalized and plural world.”

Breast Cancer After Chest Radiation Therapy for Childhood Cancer: Tara Henderson — Journal of Clinical Oncology, April 21, 2014

From the abstract: “Among women treated for childhood cancer with chest radiation therapy, those treated with whole-lung irradiation have a greater risk of breast cancer than previously recognized, demonstrating the importance of radiation volume. Importantly, mortality associated with breast cancer after childhood cancer is substantial.”

Clinical Presentation and Disease Course of Inflammatory Bowel Disease Differs by Race in a Large Tertiary Care Hospital: M. Anthony Sofia, David T. Rubin, Ningqi Hou and Joel Pekow — Digestive Diseases & Sciences, April 22, 2014

From the abstract: “While the incidence of inflammatory bowel disease (IBD) among African-Americans (AAs) is increasing, there is limited understanding of phenotypic differences and outcomes by race … We identified significant differences in disease characteristics and extraintestinal manifestations between AA and Ca IBD patients in a large tertiary care population. These results have implications for future genotype-phenotype studies.”

Burden of Total and Cause-Specific Mortality Related to Tobacco Smoking among Adults Aged ≥45 Years in Asia: A Pooled Analysis of 21 Cohorts: Habibul Ahsan — PLoS Medicine, April 22, 2014

From the abstract: “Tobacco smoking is associated with a substantially elevated risk of mortality, accounting for approximately 2 million deaths in adults aged ≥45 y throughout Asia in 2004. It is likely that smoking-related deaths in Asia will continue to rise over the next few decades if no effective smoking control programs are implemented.”

About Matt Wood (479 Articles)
Matt Wood is a senior science writer for the University of Chicago Medicine and editor of the Science Life blog.
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