LabBook June 6, 2014

UChicago microbiologist Jack Gilbert giving a lecture on "The Microbiome Revolution" at the Donnelley Biological Sciences Learning Center, June 2, 2014

UChicago microbiologist Jack Gilbert giving a lecture on “The Microbiome Revolution” at the Donnelley Biological Sciences Learning Center, June 2, 2014

This week’s rundown of recent research publications of note from University of Chicago scientists and physicians:

Thoracic Surgeons’ Perception of Frail Behavior in Videos of Standardized Patients: Mark Ferguson, Stephen Small — PLoS One

From the abstract: “Frailty is a predictor of poor outcomes following many types of operations. We measured thoracic surgeons’ accuracy in assessing patient frailty using videos of standarized patients demonstrating signs of physical frailty. We compared their performance to that of geriatrics specialists … [and] varying degrees of frailty are rated with internal consistency by thoracic surgeons as accurately as geriatrics specialists when referenced to an anchored scale. Ratings were less consistent for moderate degrees of frailty, suggesting that physicians require training to recognize early frailty.”

Low grade prostate cancer diverges early from high grade and metastatic disease: David VanderWeele, Walter Stadler, Kevin White — Cancer Science

From the abstract: “Understanding the developmental relationship between indolent and aggressive tumors is central to understanding disease progression and making treatment decisions. For example, most men diagnosed with prostate cancer have clinically indolent disease and die from other causes. Overtreatment of prostate cancer remains a concern. Here we use laser microdissection followed by exome sequencing of low and high grade prostate cancer foci from four subjects, and of metastatic disease from two of those subjects, to evaluate the molecular relationship of coincident cancer foci.”

Development and Testing of an iOS Waiting Room “App” for Contraceptive Counseling in a Title X Family Planning Clinic: Melissa Gilliam – American Journal of Obstetrics and Gynecology

From the abstract: “Long-acting reversible contraceptive (LARC) methods — the intrauterine device (IUD) and implant — are highly effective but used by <10% of United States women. We aimed to improve LARC interest by enhancing clinic counseling. A quality improvement methodology was used to evaluate IUD service delivery in three Chicago Title X clinics. To address identified barriers, we developed a theory-based iOS application (“app”) for patients to use in the clinic waiting room using human centered design.”

Dentists’ Willingness to Provide Expanded HIV Screening in Oral Health Care Settings: Results From a Nationally Representative Survey: Harold Pollack — American Journal of Public Health

From the abstract: “Using a nationally representative survey, we determined dentists’ willingness to provide oral rapid HIV screening in the oral health care setting … Agreement with the importance of annual testing for high-risk persons and familiarity with the Centers for Disease Control and Prevention’s recommendations regarding routine HIV testing were positively associated with willingness to conduct such screening. Respondents’ agreement with patients’ acceptance of HIV testing and colleagues’ improved perception of them were also positively associated with willingness.”

About Matt Wood (468 Articles)
Matt Wood is a senior science writer for the University of Chicago Medicine and editor of the Science Life blog.
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