Three University of Chicago Medicine faculty members recognized for outstanding research, teaching
Yang-Xin Fu, professor in the Department of Pathology and member of the Comprehensive Cancer Center, has been named the Fanny L. Pritzker Professor.
Fu is one of the nation’s leading investigators in the targeted treatment of tumors via local radiation, antibodies and immunotherapy. He has published more than 150 papers in these fields, many in high-impact journals, including Science, Nature Immunology and Nature Medicine. He recently has focused on translational medicine, especially on ways to mobilize the immune system to help treat cancer and infectious diseases.
Fu is a member of the American Association of Immunologists and the American Society of Clinical Pathology, and has served as an associate editor for several immunology journals. He is the primary investigator or co-investigator on numerous major National Institutes of Health grants.
He joined the University of Chicago faculty in 1998.
Rothman-Denes is best known for her pioneering work on a system to study how bacterial viruses take over the molecular processes of their hosts. Combining genetic, biochemical, biophysical and structural approaches, she has yielded fundamental insights into viral-host interactions and identified new mechanisms of regulation of gene expression at the transcriptional level. Her laboratory also focuses on further elucidating these viral-host interactions and exploiting them to discover new targets for antibacterials.
Rothman-Denes is a member of the National Academy of Sciences. She is an elected fellow of the American Association for the Advancement of Science, the American Academy of Arts & Sciences and the American Academy of Microbiology. She has taught a rigorous graduate class in molecular biology for decades, and her outstanding mentorship of both graduate and undergraduate students in her laboratory has cultivated the careers of numerous successful scientists.
She joined the University of Chicago faculty in 1974.
Roux has made seminal contributions to the field of theoretical and computational approaches toward molecular structure and function. He is a pioneer in the study of integral membrane proteins, using molecular dynamics and atomic models to help interpret and predict experimental results. His work has bridged theory and experiment in biophysics and has been critical to understanding the properties of fundamental biological systems at the physico-chemical and atomic levels.
Roux is a recipient of the prestigious Rutherford Memorial Medal in Chemistry, awarded by the Royal Society of Canada. He is a member of the Biophysical Society and serves on the editorial boards of numerous top journals.
Roux joined the University of Chicago faculty in 2005.