LabBook, February 6, 2015

Even our littlest patients are getting into the spirit of  the American Heart Association's National Wear Red Day. AHA volunteers knitted and donated red hats for new babies at Comer Children's Hospital through the Little Hats, Big Hearts initiative to raise awareness of congenital heart defects. Here, Kendra Rivers and daughter Niyella model their new headwear.

Even our littlest patients are getting into the spirit of the American Heart Association’s National Wear Red Day. AHA volunteers knitted and donated red hats for new babies at Comer Children’s Hospital through the Little Hats, Big Hearts initiative to raise awareness of congenital heart defects. Here, Kendra Rivers and daughter Niyella model their new headwear.

This week’s rundown of recent research publications of note from University of Chicago scientists and physicians:

Cerebrospinal Fluid Inflammatory Cytokines And Aggression In Personality Disordered Subjects: including Emil Coccaro and Royce Lee — International Journal of Neuropsychopharmacology

From the abstract: “Neurochemical studies have pointed to a modulatory role in human aggression for a variety of central neurotransmitters and neuromodulators such as cytokines. While animal studies of cytokines suggest an aggression facilitating role for central cytokines, especially for IL-1β and other cytokines, no cerebrospinal fluid (CSF) studies of cytokines have yet been reported in regard to human aggression … These data suggest a positive relationship between at least one inflammatory cytokine in the central nervous system and aggression in human subjects. This finding adds to the complex picture of the central neurochemistry of impulsive aggression in human subjects.”

Mediators involved in the relation between depressive symptoms and weight status in female adolescents and young adults: including Andrea Goldschmidt — International Journal of Obesity

From the abstract: “Depression may be a risk factor for overweight status, but mechanisms involved in this relationship are unclear. This study explored behavioral factors involved in the relationship between adolescent depression symptoms and adult overweight status … Binge eating may be one pathway to overweight among depressed females, suggesting that recognition and treatment of eating pathology in individuals with depression may help prevent overweight.”

Whole-grain wheat consumption reduces inflammation in a randomized controlled trial on overweight and obese subjects with unhealthy dietary and lifestyle behaviors: role of polyphenols bound to cereal dietary fiber: including Sean Gibbons and Jack Gilbert — The American Journal of Clinical Nutrition

From the abstract: “Epidemiology associates whole-grain (WG) consumption with several health benefits. Mounting evidence suggests that WG wheat polyphenols play a role in mechanisms underlying health benefits … The objective was to assess circulating concentration, excretion, and the physiologic role of WG wheat polyphenols in subjects with suboptimal dietary and lifestyle behaviors.”

About Matt Wood (468 Articles)
Matt Wood is a senior science writer for the University of Chicago Medicine and editor of the Science Life blog.
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