Research and Discoveries

Chemo-immunotherapy approach shows potential benefit in patients with advanced HPV-negative head and neck cancer
Chemotherapy and immunotherapy followed by de-escalated chemoradiation showed increased survival and reduced side effects in aggressive head and neck cancers that are not associated with human papillomavirus (HPV) infection, according to a new study.

Resilient 'SuperAgers' show the positive side of growing old
With participants ages 80 to 110, the SuperAging Research Initiative examines what's going right in the lives and brains of people who are living long and living well.

Uncovering inequalities in breast cancer immunotherapy access
New research shows that triple-negative breast cancer (TNBC) patients who are Black or have lower socioeconomic status are significantly less likely to have access to cutting-edge, life-saving treatments.

Researchers look for the best ways to help people with HIV quit smoking
Combining bupropion medication and a behavioral counseling program dramatically increased quit rates among people living with HIV who smoked.

Vitamin E succinate controls tumor growth and enhances immunotherapy effects
High levels of fat mass and obesity-associated protein (FTO) have been linked to tumor growth and resistance to immunotherapy. Researchers identified vitamin E succinate as an effective agent in controlling tumor growth by promoting the degradation of FTO.

Clinical trial to study new use for CAR T-cell therapy: treating autoimmune diseases
The University of Chicago Medicine has launched a Phase 2 clinical trial to study how CAR T-cell therapy could be used to treat three autoimmune diseases.

Fine-tuned brain-computer interface makes prosthetic limbs feel more real
Two new papers document progress in neuroprosthetic technology that lets people feel the shape and movement of objects moving over the "skin" of a bionic hand.

An alternative to knee replacement surgery? NIH-funded study is testing a procedure for osteoarthritis knee pain
University of Chicago Medicine doctors are studying whether blocking off targeted arteries can help patients with knee pain who do not want or cannot have knee replacement surgery.