Research and Discoveries

Tumor byproduct blocks immune cells from fighting cancer
Researchers from the University of Chicago and the University of Pittsburgh have identified a novel oncometabolite that accumulates in tumors and impairs immune cells’ ability to fight cancer.

Global telemedicine therapy for dementia shows benefit
Clinical trial results indicate that primary progressive aphasia (PPA) patients and their communication partners benefit from remote speech-language therapy.

Understanding how laughing gas can fight depression
Study in mice helps explain the mechanisms by which nitrous oxide affects the brain, potentially offering insights that could help relieve treatment-resistant depression.

AI helps find promising therapeutic target for rare salivary gland cancer
Researchers have uncovered a promising therapeutic target for adenoid cystic carcinoma (ACC), a rare cancer of the salivary glands with few treatment options. The study found that blocking the activity of protein arginine methyl transferase 5 (PRMT5) is a potential treatment strategy against ACC.

Chemo-immunotherapy approach shows potential benefit in patients with advanced HPV-negative head and neck cancer
Chemotherapy and immunotherapy followed by de-escalated chemoradiation showed increased survival and reduced side effects in aggressive head and neck cancers that are not associated with human papillomavirus (HPV) infection, according to a new study.

Resilient 'SuperAgers' show the positive side of growing old
With participants ages 80 to 110, the SuperAging Research Initiative examines what's going right in the lives and brains of people who are living long and living well.

Uncovering inequalities in breast cancer immunotherapy access
New research shows that triple-negative breast cancer (TNBC) patients who are Black or have lower socioeconomic status are significantly less likely to have access to cutting-edge, life-saving treatments.

Researchers look for the best ways to help people with HIV quit smoking
Combining bupropion medication and a behavioral counseling program dramatically increased quit rates among people living with HIV who smoked.